Iga Swiatek beat unseeded Jule Niemeier to reach her first quarter-final in New York.
Swiatek fought back to win 2-6 6-4 6-1 against the German.
She has been the standout WTA player this season and is bidding for a seventh title in 2022.
The reigning French Open champion will play American Jessica Pegula, who beat Czech 21st seed Petra Kvitova.